Hall was hurt on a tackle between Denver Broncos defenders Pat Surtain II and Jonas Griffith. Hall immediately went into the medical tent. He began walking toward the locker room with trainers before being carted from the sideline.
He had four carries for 72 yards before leaving. Hall entered the game with 609 yards from scrimmage, the most by any Jets player in the team’s first six games since Curtis Martin in 2004.
Head coach Robert Saleh said post-game that the team's fear is that Hall suffered an ACL injury.
Hall tweeted after the game: "Resilient! Through all the trials and tribulations JETS WIN!!!!!!"
"Appreciate the endless love and support! Another step along the journey, see y’all soon," Hall tweeted.
"He's in good spirits. He understands that this is a small chunk of his story" running back and teammate Michael Carter said.
The Jets also announced in the third quarter that right tackle Alijah Vera-Tucker (elbow) was ruled out. Wide receiver Corey Davis (knee) was questionable to return.
Vera-Tucker was also ruled out of the year Monday due to a triceps injury that will require surgery.
The Jets are 5-2 on the year, just behind the Buffalo Bills (5-1) for first place in the AFC East.
The Associated Press contributed to this report